B Vitamins, including B6, B9 (folate), and B12, play essential roles in the brain's neurotransmitter synthesis, influencing mood and stress levels. They are often included in stress-relief supplements because they can enhance the effectiveness of neurotransmitters like serotonin, norepinephrine, and dopamine. Aside from their calming effects, B Vitamins are crucial for various metabolic processes, energy production, and the formation of red blood cells. They are naturally found in foods like leafy greens, whole grains, and animal products. B Vitamins are water-soluble and generally considered safe, but excessive supplementation, particularly with B6, can lead to nerve damage over time. As always, consult a healthcare provider before beginning a new supplement regimen, especially if you are pregnant or nursing.